A tricyclic antidepressant with a relatively short latency period. It has almost no sedative effect. therapeutical indications include: depressive phases of a manic-depressive psychosis, all other forms of endogenous depression (reactive and neurotic). In combination with amitriptyline it is used for depressions that occurred during treatment with reserpine. In combination with neuroleptics, it is used in the treatment of depression that developed during treatment of schizophrenic psychoses.

Exforge the combined antihypertensive which includes amlodipine and valastran. Valsartan - a specific blocker of AT1 receptors of angiotensin II. Amlodipin - calcium channel blocking agents of III generation, inhibits transmembrane receipt of Ca2+ in cardiomyocytes and smooth muscle cells of vessels, by weakening them.

Calcium channel blocker, a derivative of 1,4-dihydropyridine, has a predominantly cerebrovasculative and antiischemic action. Prescribed for the prevention and treatment of brain ischemia on the background of subarachnoid hemorrhage caused by aneurysm rupture, expressed by brain disfunction in the elderly patients. It can prevent or eliminate spasm of vessels caused by various vasoconstrictor drugs. Improves stability and functional capacity of neurons.