Sinemet - a combined remedy based on Levodopum + Carbidopum. In the treatment of Parkinson's syndrome and disease, Sinemet proved to be one of the most effective drug. The reviews are mostly positive, because it allows to reduce "inhibition" in patients who have been treated with other medications. For each patient, the dosage is selected individually, together with the frequency of admission.
Sinemet
Package | pill | Total price | Save | Order |
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500mg × 30 Pills | $2.47 | $74.06 + Bonus - 4 Pills | - | Add to cart |
500mg × 60 Pills | $2.02 | $121.02 + Bonus - 4 Pills | $27.00 | Add to cart |
500mg × 90 Pills | $1.93 | $174.03 + Bonus - 7 Pills | $48.60 | Add to cart |
500mg × 120 Pills | $1.88 | $225.03 + Bonus - 7 Pills Free Trackable Delivery | $70.80 | Add to cart |
500mg × 180 Pills | $1.81 | $326.07 + Bonus - 11 Pills Free Trackable Delivery | $118.80 | Add to cart |
500mg × 360 Pills | $1.75 | $629.04 + Bonus - 11 Pills Free Trackable Delivery | $259.20 | Add to cart |
Package | pill | Total price | Save | Order |
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300mg × 30 Pills | $2.46 | $73.87 + Bonus - 4 Pills | - | Add to cart |
300mg × 60 Pills | $2.07 | $124.37 + Bonus - 4 Pills | $23.40 | Add to cart |
300mg × 90 Pills | $1.94 | $174.88 + Bonus - 7 Pills | $46.80 | Add to cart |
300mg × 120 Pills | $1.88 | $225.38 + Bonus - 7 Pills Free Trackable Delivery | $69.60 | Add to cart |
300mg × 180 Pills | $1.81 | $326.38 + Bonus - 11 Pills Free Trackable Delivery | $117.00 | Add to cart |
300mg × 270 Pills | $1.77 | $477.88 + Bonus - 11 Pills Free Trackable Delivery | $186.30 | Add to cart |
300mg × 360 Pills | $1.75 | $629.39 + Bonus - 11 Pills Free Trackable Delivery | $255.60 | Add to cart |
Package | pill | Total price | Save | Order |
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250mg × 30 Pills | $2.07 | $62.09 + Bonus - 4 Pills | - | Add to cart |
250mg × 60 Pills | $1.70 | $102.06 + Bonus - 4 Pills | $22.20 | Add to cart |
250mg × 90 Pills | $1.50 | $135.04 + Bonus - 7 Pills | $51.30 | Add to cart |
250mg × 120 Pills | $1.34 | $161.08 + Bonus - 7 Pills | $87.60 | Add to cart |
250mg × 180 Pills | $1.13 | $203.04 + Bonus - 11 Pills Free Trackable Delivery | $169.20 | Add to cart |
250mg × 360 Pills | $0.98 | $351.01 + Bonus - 11 Pills Free Trackable Delivery | $392.40 | Add to cart |
Package | pill | Total price | Save | Order |
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110mg × 30 Pills | $1.26 | $37.80 + Bonus - 4 Pills | - | Add to cart |
110mg × 60 Pills | $1.03 | $61.99 + Bonus - 4 Pills | $13.80 | Add to cart |
110mg × 90 Pills | $0.96 | $86.18 + Bonus - 7 Pills | $27.00 | Add to cart |
110mg × 120 Pills | $0.92 | $110.38 + Bonus - 7 Pills | $40.80 | Add to cart |
110mg × 180 Pills | $0.88 | $158.76 + Bonus - 11 Pills | $68.40 | Add to cart |
110mg × 270 Pills | $0.86 | $231.34 + Bonus - 11 Pills Free Trackable Delivery | $108.00 | Add to cart |
110mg × 360 Pills | $0.84 | $303.91 + Bonus - 11 Pills Free Trackable Delivery | $151.20 | Add to cart |
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Sinemet Product Description
Drug Uses
Sinemet is a combination drug related to a therapeutic class known as antiparkinsonian agents. Sinemet is used to manage rare and more common forms of parkinsonism or parkinsonian syndrome, such as:
Parkinson's disease (PD)
Symptomatic and post-encephalitic parkinsonism
Sinemet stops or reduces progression of parkinsonism symptoms, including symptoms that can result in disability. This effect is achieved because Sinemet improves the process of replenishing dopamine in the brain.
At the beginning of the parkinsonian syndrome treatment, one tablet of Sinemet 25/ 100mg should be taken, three times a day. The dosage can be increased by one tablet every 24 or 48 hours till the maximum recommended daily Sinemet dosage of eight 25/100mg tablets is achieved.
Missed dose
If you’ve missed the assigned dosage of Sinemet, take the antiparkinsonian agent as soon as you remember. However, do not take Sinemet if it is time for the next prescribed dosage of this drug. Return to regular dosing schedule of Sinemet on the next day.
More Information
Combined dopaminergic drug Sinemet starts acting within first days of treatment, and sometimes even after the first dose intake. The clinically significant antiparkinsonian effect is achieved within 7-10 days after initiating Sinemet-therapy.
Storage
Antiparkinsonian agent Sinemet should be protected from strong light and excessive moisture under 30°C, and kept in an original package thoroughly sealed.
Sinemet Safety Information
Warnings
Sinemet should not be used if movement disorders, changes in behavior, hyperkinesia, and other extrapyramidal reactions were caused by drugs. In rare cases, the use of combined dopaminergic drug Sinemet may cause severe drowsiness, even in the middle of the day. Usually involuntary sleep episodes appear at the beginning of the parkinsonism treatment.
Disclaimer
Information about treatment of Parkinson's disease, provided in this review of Sinemet, is offered only “as-is” for informational and educational purposes only. This information is not implied to be a substitute for professional medical advice of the neurologist, neurosurgeon or other medical professional. The online pharmacy shall not be liable for any injury, which may be caused by improper use of the information on antiparkinsonian agent Sinemet.
Sinemet Side Effects
Most adverse reactions of Sinemet are mild and normally disappear after the daily dosage of the antiparkinsonian agent is decreased. The most often Sinemet may cause in the patients with parkinsonism such reactions as dyskinesia, chest pain, low blood pressure, vomiting, gastrointestinal bleeding, nausea, angioedema, shortness of breath, flushing, loss of hair, back pain or shoulder pain.
In rare cases, the patients taking Sinemet complain of: asthenia, anorexia, diarrhea, dark saliva, palpitation, muscle cramps, low platelet count, urticaria, pruritus, dizziness, somnolence, urinary tract infection or swelling.
Amaryl - a medicine of group of sulphonylurea, the peroral hypoglycemic medicine. It has an initially prolonged effect. The mechanism of action consists in stimulation of secretion and release of insulin from beta cells of a pancreas (pancreatic effect). It also increases sensitivity of fatty and muscular tissues to effect of insulin (extrapancreatic effect).
Cialis Soft Tabs differs from a usual tablet of Cialis in the fact that its action comes quicker. Cialis Soft is chewed and dissolved under a tongue that allows to reach a required effect in 10-15 minutes. Important!!! Cialis Soft is compatible to alcohol and greasy food!
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Celexa - antidepressant. Brings energy, stops feeling of alarm, reduces sensation of fear and tension, eliminates dysphoria, reduces persuasive feelings, practically does not cause sedation. The lasting clinical effect develops in 7-10 days of regular reception. The mechanism of action is connected with selective blockade of the return neuronal serotonin reuptake in synapses of neurons of CNS with a minimum effect concerning reuptake of noradrenaline and dopamine.
The medicine belongs to the group of cardiac glycosides. The preparation obtained from the medicinal plants' Woolly Foxglove. It has the following actions: inotropic, vasodilator and moderate diuretic. The pills increase the concussive and systolic volume of the heart, increases the refractory period, reduces atrioventricular conduction, reduces the frequency of contractions of the heart muscle. In the case of stagnation in cardiovascular insufficiency, it has a pronounced vasodilating effect. Lanoxin has a mild diuretic effect, reduces the severity of edema. Overdosage may trigger an increase in the excitability of the myocardium, resulting in disturbances of heart rhythm.
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Keppra - antiepileptic drug, the mechanism of action is unclear, it does not alter normal synaptic transmission. Effective in both focal and epilepsy (epileptiform manifestations, photo paroxysmal reaction).
Peripheral vasodilator with predominant effect on venous vessels. It is used for the prevention of angina in CHF, hypertension in the "small" circulation, "pulmonary" heart (treatment as a part of combination therapy), spasm of peripheral arteries (obliterating endarteritis, angiospastic retinitis)
Xeloda is a cytostatic drug. The drug is used for the treatment of patients with metastatic or locally advanced breast cancer, including after an ineffective chemotherapy course, which included anthracycline drugs and taxanes, and also if the patient has contraindications to anthracyclines.
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