Adalat, which is nifedipine - belongs to hypotensive medicine with antianginalny activity. Blocking calcic channels, an active component of Adalat (nifedipine) causes decrease in intracellular concentration of ions of calcium in smooth muscle cell of intima of vessels and cardiocyte, causing vasodilatory action - in particular, on coronary vessels. As a result of decreases systolic blood pressure, falls TPR and decreases afterload on cardiac muscle. Except for normalization of a coronary blood flow, Adalat promotes pressure decrease in system of pulmonary artery, improves cerebral haemo dynamics. Long-term taking of medicine guarantees anti-atherogenous action, prevents thrombocyte aggregation.
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Calcium channel blocker, a derivative of 1,4-dihydropyridine, has a predominantly cerebrovasculative and antiischemic action. Prescribed for the prevention and treatment of brain ischemia on the background of subarachnoid hemorrhage caused by aneurysm rupture, expressed by brain disfunction in the elderly patients. It can prevent or eliminate spasm of vessels caused by various vasoconstrictor drugs. Improves stability and functional capacity of neurons.
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