Anafranil, which is clomipramine - is a tricyclic antidepressant. Clomipramine has antiserotonin effect, it eliminates night enuresis, causes loss of appetite. Sedative action is shown due to linkng with H1-histamine receptors, blocking of alpha-adrenoceptors. Medicine eliminates arrhythmia, slows down ventricular conductivity. The anti-depressive effect is implemented due to increase in concentration of noradrenaline, serotonin in synapses because of weakening of the process of recapture of these substances by presynaptic neurons.
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